Centralisation of post-resuscitation care after out-of-hospital cardiac arrest at heart centres - a nationwide follow-up study

Abstract Funding Acknowledgements Type of funding sources: None. Background Recent guidelines recommend centralisation post-resuscitation care in out-of-hospital cardiac arrest (OHCA) patients dedicated Cardiac Arrest Centres (CACs) aiming to improve outcome. Purpose To describe the process implementation policy and impact on 30-day mortality rate. Methods This nationwide study included all adult OHCA (>18 years) based Danish Registry. Centralisation was introduced 2009, 2010, 2012 four regions (A, B, C, D), one region has not yet implemented (control). Parallel trends assumption made a difference-in-difference model with repeated cross-sections used estimate average treatment effect treated patients. The compared between living that versus control without centralisation. Results A total 20,566 were identified 2007 2020. majority 50 75 years (53.7%) 67.8% male. Bystander cardiopulmonary resuscitation performed 55.3%. Shockable rhythm present 34.6% CACs been gradually completely (Figure 1A). Patients shockable rhythms (72%), younger < (64%) more frequently transported CACs. lower among 1B). significantly improved survival by 6% (95% CI: 2%-10%) percentage points after controlling for known covariates (sex, age, Charlson Comobidity Index, rhythm, bystander resuscitation). Conclusions In this study, over time. Although, favorable prognostic factors CACs, increased 6 absolute points.